Shift Work Disrupts Circadian Rhythm and Mitochondrial Quality Control in the Heart
As part of our Monday seminar series, we are delighted to welcome our speaker:
Talk title: Shift Work Disrupts Circadian Rhythm and Mitochondrial Quality Control in the Heart
Dr. Lorrie Kirshenbaum
Director, Institute of Cardiovascular Sciences, St. Boniface Hospital Albrechtsen Research Centre
Department of Physiology and Pathophysiology,
University of Manitoba
Hosted By
How to join
The event will be in person only, no need to register.
MSB 2172
Medical Sciences Building
University of Toronto
1 King’s College Circle
Toronto, ON M5S 1A8
If you have any questions about this event, please contact Debb Yorke at lmp.chairadmin@utoronto.ca.
Speaker: Dr. Lorrie A. Kirshenbaum
Dr. Lorrie A. Kirshenbaum is Director of the Institute of Cardiovascular Sciences at the St. Boniface Hospital Albrechtsen Research Centre, Canada Research Chair in Molecular Cardiology, Professor and Division Head of Cardiovascular Science and Disease, Department of Physiology and Pathophysiology and Director of Research Development at the Max Rady College of Medicine, Rady Faculty of Health Sciences at the University of Manitoba in Winnipeg Canada.
A major focus of Dr. Kirshenbaum’s research over the past 30 years has been directed toward understanding the molecular signaling pathways that underlie sex specific differences in the pathogenesis of heart failure. Dr. Kirshenbaum’s major contributions include his early pioneering work mechanism of programmed cell death in the heart and the role of Bcl-2 gene family proteins. His lab was among one of the first to delineate a role for Bcl-2 as an anti-death gene in the heart, as well as Bnip3 as a key regulator of mitochondrial dysfunction cell death during hypoxic and ischemic stress. Dr. Kirshenbaum’s most recent contributions include his work on circadian regulated cellular quality control mechanisms and chemotherapy- induced cardiotoxicity.
For his contributions, Dr. Kirshenbaum has received several prestigious honors and awards including the recognition by the Province of Manitoba with the Order of Manitoba, the Dr. John Bowman Rh Award from the University of Manitoba for outstanding contributions to medical research, the James T. Willerson Award for Excellence in Cardiovascular Sciences from the International Academy of Cardiovascular Sciences, as well as many others accolades from different agencies.
Dr. Kirshenbaum serves on many journal editorial boards and international grant review committees, board of directors for different agencies, as well as national and international societies and peer review grant panels including, Canadian Institutes of Health Research, Heart and Stroke Foundation of Canada, American Heart Association and has served as the chair of the NIH study sections and most recently was the organizing chair of the 2022 NAS ISHR meeting in Winnipeg, Canada.
