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Graduate course list
- LMP1001/1002/1003: Graduate Seminars in Laboratory Medicine and Pathobiology
- LMP1005H: Fundamentals of Research Practice
- LMP1100H: Cellular imaging in pathobiology
- LMP1101H: Basic concepts in inflammatory/autoimmune arthritis
- LMP1102H: Clinical concepts in inflammatory/autoimmune arthritis
- LMP1103H: Tissue injury, repair and regeneration
- LMP1105: Current understanding of Atherosclerosis
- LMP1106H: Molecular Biology Techniques
- LMP1107H: Bioinformatics in LMP
- LMP1108H: Genome analysis in medicine
- LMP1110H: Neural Stem Cells - brain development and maintenance
- LMP1111: Introduction to R and the Analysis of Single Cell Data
- LMP1200H: Neoplasia
- LMP1203H: Basic principles of analytical clinical biochemistry
- LMP1206H: Next generation genomics in clinical medicine
- LMP1207H: Mass spectrometry, proteomics and their clinical applications
- LMP1208H: Molecular clinical microbiology and infectious diseases
- LMP1210H - Basic Principles of Machine Learning in Biomedical Research
- LMP1211H: Foundations in Musculoskeletal Science
- LMP2004H: Introduction to Biostatistics
- Fees, stipends, awards & grants
- Program transfers
- LMP Workshop Program
- Time off, leave and withdrawals
- Academic appeals
- Program completion for MSc and PhD
- Graduate forms
- Student services and support
- Communicate your research: the 3MT in LMP
- Mentoring & professional development for graduate students
- Master of Health Science (MHSc) in Laboratory Medicine
- Master of Science in Applied Computing (MScAC) Artificial Intelligence in Healthcare
- Collaborative Specialization in Musculoskeletal Sciences (CSMS)
- Master of Health Science (MHSc) in Translational Research
- Student Union: CLAMPS
Breadcrumbs
LMP1108H: Genome analysis in medicine
Who can attend
There are no prerequisites for this course.
Course description
The advent of next-generation sequencing technologies coupled with decreasing cost has accelerated the pace of gene discovery and revolutionized DNA based diagnostics.
You will become familiar with current methods in the analysis and medical interpretation of genomic sequence data.
By the end of this course you will understand how to:
- analyze a genome
- interpret a genome
You will follow the steps of genomic analysis and complete assignments each week that use the resources we discuss in lectures.
You will complete a term project to analyze a raw genome sequence and report on the relevant findings.
Course coordinators
Dr. Christian Marshall
crm@sickkids.ca
Dr. Michelle Axford
michelle.axford@sickkids.ca
lmp.grad@utoronto.ca for administrative queries.
Timings and location
This course is offered every odd year in the Winter session (i.e. 2021, 2023 etc).
Thursdays 1 – 4 pm
Location: Online
Evaluation methods
Weekly assignments - 50%
Term project - 50%
Schedule
Date |
Topic |
Lecturer/instructor |
---|---|---|
March 6, 2025 |
Genome Structure and Variation |
|
March 13, 2025 |
Genome Sequencing Methodologies |
|
March 20, 2025 |
No class |
|
March 27, 2025 |
Informatics Approaches to Genomic Analysis |
|
April 3, 2025 |
Genome Filtering, Interpretation, and Reporting |
|
April 10, 2025 |
Medical and Diagnostic Applications of Genome Analysis |
|
April 17, 2025 |
Term Project Discussion |