Mohamed Abouelhassan

I was born in the historical city of Alexandria in the northern coast of Egypt. I obtained a B.Sc. and a M.Sc. from Egypt and Ph.D. (Biochemistry) from the Netherlands. I obtained my Clinical Chemistry education from the Clinical Chemistry program at the University of Toronto. 

I am extremely passionate about teaching. Besides teaching at the University of Toronto, I hold an Assistant Professor appointment at the University of Dalhousie and currently teaches in the Department of Pathology.

I have a long lasting interest in applied and basic research and is currently interested in studying the role of diurnal variation in the clinical utility of clinical chemistry analytes. I am also a member of the Dalhousie Myeloma Research Group with an interest in studying genetic and epigenetic changes associated with multiple myeloma progression and relapse. 

I am also interested in pursuing other professional activities. I participated in Canadian programs aimed to increase the public awareness of medical research such as Experts-on-Demand, Canada Wide Science Fair and Virtual Researcher on Call (VROC).  Furthermore, I volunteered as the Website Editor of the Canadian Society of Clinical Chemistry (CSCC) and recently accepted the role of Chair of CSCC Abstract Review Committee.

Research Synopsis

I am currently interested in studying the role of diurnal variation in the clinical utility of clinical chemistry analytes. I am also a member of the Dalhousie Myeloma Research Group. I am interested in studying genetic and epigenetic changes associated with multiple myeloma progression and relapse.

Recent Publications

M. Elnenaei, P. Knopf P, S. Cutler, K. Sinclair, M. Abou El Hassan, W. Greer, M. Goudie, J. Wagner, D. White, S. Couban, N. Forward, D. Gaston, C. Campbell. Low-Depth Sequencing for Copy Number Abnormalities in Multiple Myeloma Supersedes Fluorescent in Situ Hybridization in Scope and Resolution. Clinical Genetics 96 (2019) 163

M. Abou El Hassan, E. Delvin, M. Elnenaie, B. Hoffman. Diurnal rhythm in clinical chemistry: An underrated source of variation. Critical Reviews in Clinical Laboratory Sciences 55 (2018) 516

M. Abou El Hassan, K. Huang, Z. Xu, T. Yu, R. Bremner. Frequent IRF1 Binding at Remote Elements without Histone Modification. J Biological Chemistry. 293(26):10353.

M. Abou El Hassan, K. Huang, Z. Xu, M. B. K. Eswara, T. Yu, Z. Ni, I. Livne-bar, M. Sangwan, M. Ahmad and R. Bremner. Properties of STAT1 and IRF1 Enhancers and the Influence of SNPs. BMC Molecular Biology. 18 (2017) 6.

M. Abou El Hassan, D. Lin, T. Earle, M. Millar, I. M. Blasutig. Analytical evaluation of the BioPlex® 2200 25-OH Vitamin D total assay. Clin Biochem. 49 (2016) 723-5.

M. Abou El Hassan, A. Stoianov, P.A. Araújo, T. Sadeghieh, M.K. Chan MK, Y. Chen, E. Randell, M. Niewesteeg, K. Adeli. CLSI-based transference of CALIPER pediatric reference intervals to Beckman Coulter AU biochemical assays. Clin Biochem. 48 (2015) 1151-9.

M. Abou El Hassan, K. Huang, M. B. K. Eswara, M. Zhao, L. Song,T. Yu, Y. Liu, J. Liu, S. McCurdy, A. Ma, J. Wither, J. Jin, E.Zacksenhaus, J. L. Wrana and R. Bremner. Cancer Cells Hijack PRC2 to Modify Multiple Cytokine Pathways. Plos One. 10 (2015) e0126466.

M. Abou El Hassan, T. Yu, L. Song, R. Bremner. Polycomb Repressive Complex 2 Confers BRG1 Dependency on the CIITA Locus. J Immunol. 194 (2015) 5007-5013.

M. Abou El Hassan, E. P. Diamandis, S. A. Karumanchi, A. H. Shennan, R. N. Taylor. Preeclampsia: An Old Disease with New Tools for Better Diagnosis and Risk Management. Clin Chem. 61 (2015) 694-698.

K. H. T. Leung, M. Abou El Hassan and R. Bremner. A rapid and efficient method to purify proteins at replication forks under native conditions. BioTechniques, 55 (2013) 204–206.