Case of the Month: March 2024

Clinical history

A 35-year-old female patient has an asymptomatic thyroid mass that was diagnosed 6 years ago as a 10 mm “cyst” that was followed by surveillance. It recently became larger in size, to “almost double the size”, and prompted the patient to seek medical care. Thyroid hormone and TSH levels were within normal limits, and there was no cervical lymphadenopathy. The physical examination revealed a palpable neck mass on the left side of the neck, but was otherwise unremarkable. Ultrasound showed a left 2.0 x 1.7 cm mass, TIRADS 4. The patient underwent a fine needle aspiration of the thyroid mass.

Questions:

  • How are thyroid cytology specimens reported by pathologists? 

  • How would you describe the cells in this cytology sample?

  • What is your differential diagnosis?

How to participate

Take a look at the images.

Anyone is welcome to try to solve the puzzle by commenting on the related post on our Instagram.

If you are a medical student at the University of Toronto, you can also:

If you do, you are in for a chance to win a $100 gift card! (UofT Med students only).

If you are a current medical student at U of T, you can register to join the March case of the month lecture online or in person and have a chance to win a $100 gift card!

You can also join the Special Interest Group in Laboratory Medicine to learn more about Laboratory Medicine.